Article

The Cancer Stem Cell Theory: Is It Correct?

2008-11-01

Abstract excerpt

The cancer stem cell hypothesis posits that tumor growth is driven by a rare subpopulation of cells, designated cancer stem cells (CSC). Studies supporting this theory are based in large part on xenotransplantation experiments wherein human cancer cells are grown in immunocompromised mice and only CSC, often constituting less than 1% of the malignancy, generate tumors. Herein, we show that all colonies derived fro...

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Literature Corpus work: a8ca45a5-a5ba-5e7f-b56e-0648741c09fd
DOI: 10.1016/s1016-8478(23)14031-3

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