Article

LNP-CpG: deploy the self-adjuvant role of mRNA vaccines

2026-08-23

Abstract excerpt

With the rapid advancement of mRNA vaccines, lipid nanoparticles (LNPs) have emerged as pivotal carriers and adjuvants for non-mRNA vaccine modalities, driven by their superior nucleic acid delivery efficiency and intrinsic self-adjuvanting properties. In this study, we systematically evaluated various formulation strategies combining LNPs and the CpG adjuvant within a varicella-zoster virus glycoprotein E (VZV-gE...

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Literature Corpus work: 1f9d3f28-5ccb-5f71-877b-15011cf9ee0a
DOI: 10.64898/2026.08.19.745633

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