Article

The regulatory effect of Ca2+/calmodulin dependent protein kinase II mediated by receptor interacting protein kinase 3 on necroptosis of hypertrophic cardiomyocytes

2025-09-30

Abstract excerpt

Receptor interacting protein kinase 3 (RIPK3) plays a crucial role in the signaling pathway of necroptosis and calcium/calmodulin dependent protein kinase II (CaMKII) is a novel substrate for RIPK3 induced necroptosis. The aim of this study is to investigate the regulation and mechanism of RIPK3 on AngII induced cardiomyocyte hypertrophy.AngII was used to stimulate myocardial cells for 72 hours, inducingcardiomyoc...

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Literature Corpus work: a8bdd0ed-84f0-5475-a58e-a3737e5099b9
DOI: 10.1101/2025.09.29.679355

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