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Article

Pyroptosis and Its Regulation in Diabetic Cardiomyopathy

25 Jan 2022

Abstract excerpt

Diabetic cardiomyopathy (DbCM) is a prevalent disease, characterized by contractile dysfunction and left ventricular hypertrophy. Patients with DbCM have high morbidity and mortality worldwide. Recent studies have identified that pyroptosis, a kind of cell death, could be induced by hyperglycemia involved in the formation of DbCM. This review summarizes the regulatory mechanisms of pyroptosis in DbCM, including...

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PMID: 35145423
DOI: 10.3389/fphys.2021.791848

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