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Cardiac Troponin I R193H Mutation Is Associated with Mitochondrial Damage in Cardiomyocytes.

DNA and cell biology - 1 Feb 2021

Luo Jing, Zhao Weian, Gan Yi, Pan Bo, Liu Lingjuan, Liu Zhenguo, Tian Jie

Abstract excerpt

Malfunction of myocardial mitochondria plays a crucial role in the development of cardiovascular disorders, especially hypertrophic and dilated cardiomyopathies. Cardiac troponin I (cTnI) is an important structural protein and essential to contraction and relaxation of cardiomyocytes. Recent studies suggest that mutated cTnIR193H could function as a regulatory molecule for other cell functions. This study was to...

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Identifiers

PMID: 33465007
DOI: 10.1089/dna.2020.5828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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