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Necroptosis: a significant and promising target for intervention of cardiovascular disease

21 Apr 2025

Abstract excerpt

Due to changes in dietary structures, population aging, and the exacerbation of metabolic risk factors, the incidence of cardiovascular disease continues to rise annually, posing a significant health burden worldwide. Cell death plays a crucial role in the onset and progression of cardiovascular diseases. As a regulated endpoint encountered by cells under adverse stress conditions, the execution of necroptosis is...

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PMID: 40268251
DOI: 10.1016/j.bcp.2025.116951

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