Back to search

Article

Apelin-13 in the paraventricular nucleus protects myocardium from ischemia via V1a receptor of the paraventricular nucleus and GABAA receptor γ2 of the nucleus tractus solitarii in rats

2024-10-27

Abstract excerpt

<h4>Background</h4> Apelin system plays a significant role in central blood pressure regulation, but its role in neural control of myocardial injury protection is poorly understood. Thus, this study was undertaken to evaluate the effects of apelin-13 in the paraventricular nucleus (PVN) on myocardial infarction (MI) and ischemia/reperfusion (I/R). <h4>Methods</h4> The cardiac functions were assessed after microi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e5ce1286-3024-5ec6-af0c-1010efe8ab12
DOI
10.1101/2024.10.23.619957
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Apelin-13 in the paraventricular nucleus protects myocardium from ischemia via V1a receptor of the paraventricular nucleus and GABAA receptor γ2 of the nucleus tractus solitarii in ratsDOI 10.1101/2024.10.23.619957
Mechanisms of Cardiovascular Homeostasis and Pathophysiology – From Gene Expression, Signal Transduction to Cellular Communication –Semantic proximity
Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?Semantic proximity
Vagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling.Semantic proximity
The regulatory effect of Ca2+/calmodulin dependent protein kinase II mediated by receptor interacting protein kinase 3 on necroptosis of hypertrophic cardiomyocytesSemantic proximity
A network map of apelin-mediated signalingSemantic proximity
Atrial Natriuretic Peptide Prohormone Gene Expression: Hormones and Diseases That Upregulate its ExpressionSemantic proximity
Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H19Semantic proximity
Comprehensive insights into the function and molecular and pharmacological regulation of neuron-derived orphan receptor 1, an orphan receptorSemantic proximity
Phenotypic Shifts in Neurons of the Dorsal Motor Nucleus of the Vagus Resulting from Chronic Cardiac IschemiaSemantic proximity
The Shexiang Baoxin Pill Protects Myocardial Cells from Multiple Targets of MIRI through the PI3K/Akt/eNOS Signal PathwaySemantic proximity
Integrated analysis reveals neuro-immune pathway in the central nervous system that supports SGLT2i’s protective effects in treatment of cardiac remodelingSemantic proximity
Two Specialized Intrinsic Cardiac Neuron Types Safeguard Heart Homeostasis and Stress ResilienceSemantic proximity
Select a neighboring publication to make it the new centre.