Article

LRRK2 Deficiency Protects Hearts from Myocardial Infarction Injury in Mice via the P53/HMGB1 Pathway

2021-11-17

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>LRRK2 is a Ser/Thr kinase with multiple functional domains. Current studies have shown that its mutations are closely related to hereditary Parkinson's disease. However, its role in cardiovascular disease, especially in myocardial infarction, is unclear. The aim of this study was to explore the functional role of LRRK2 in myocardial infarction. <bold>Methods:</bold...

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Literature Corpus work: f8178a8d-6200-5b15-a657-db9e7f3aab0c
DOI: 10.21203/rs.3.rs-1060272/v1

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