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Ex Vivo Drug Responses and Molecular Profiles of 597 Pediatric Acute Lymphoblastic Leukemia Patients

2024-12-20

Abstract excerpt

Ex vivo drug response profiling is emerging as a valuable tool for identifying drug resistance mechanisms and advancing precision medicine in hematological cancers. However, the functional impact of dysregulation of the epigenome and transcriptome in this context remains poorly understood. In this study, we combined ex vivo drug sensitivity profiling with transcriptomic and epigenomic analyses in diagnostic sample...

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Literature Corpus work
a8ad04cb-3fcf-549f-b8e9-b3c72bfb1023
DOI
10.1101/2024.12.17.24319138
Open publication

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Ex Vivo Drug Responses and Molecular Profiles of 597 Pediatric Acute Lymphoblastic Leukemia PatientsDOI 10.1101/2024.12.17.24319138
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