Article
Childhood acute lymphoblastic leukemia.
Reviews in clinical and experimental hematology - 1 Jun 2002
Pui Ching-Hon, Relling Mary V, Campana Dario, Evans William E
Abstract excerpt
As cure rates in childhood acute lymphoblastic leukemia reach 80%, emphasis is increasingly placed on the accurate identification of drug-resistant cases, the elucidation of the mechanisms involved in drug resistance and the development of new therapeutic strategies targeted toward the pivotal molecular lesions. Pharmacodynamic and pharmacogenomic studies have provided rational criteria for individualizing...
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