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Evasion of serum antibodies and complement by <i>Salmonella</i> Typhi and Paratyphi A

2025-01-20

Abstract excerpt

Nontyphoidal and enteric fever serovars of Salmonella enterica display distinctive interactions with serum antibodies and the complement system, which initiate the host immune response to invading microbes. This study examines the contributions of lipopolysaccharide O-antigen and the S. Typhi Vi polysaccharide capsule to serum resistance, complement activation and deposition, and immunoglobulin (Ig) binding in n...

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Identifiers and source

Literature Corpus work
a848e569-d05b-51e9-843a-ff381a3b5a66
DOI
10.1101/2025.01.20.633845
Open publication

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