Article
Vi-deficient and nonfimbriated mutants of Salmonella typhi agglutinate human blood type antigens and are hyperinvasive.
FEMS microbiology letters - 1 Apr 1998
Miyake M, Zhao L, Ezaki T, Hirose K, Khan A Q, Kawamura Y, Shima R, Kamijo M, Masuzawa T, Yanagihara Y
Abstract excerpt
We generated nonfimbriated mutants from both Vi-positive and -negative Salmonella typhi to analyze the role of type 1 fimbriae and Vi-antigen in bacterial invasion. A Vi-defective mutant of S. typhi GIFU 10007-3 was more invasive than the wild-type strain GIFU 10007. The wild-type strain expressing Vi-antigen did not agglutinate both Saccharomyces cerevisiae and human erythrocytes but Vi-defective mutants were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.