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Host-Pathogen Interactions: Redefining the Basic Concepts of Virulence and Pathogenicity

1 Aug 1999

Abstract excerpt

While preparing to teach the Microbial Pathogenesis graduate course at our institution, we found ourselves struggling to find basic definitions of virulence and pathogenicity that incorporated the contributions of both the host and the pathogen. The generally used definition of a pathogen as a microbe that causes disease in a host (Table 1) seemed inadequate, because some microbes do not cause clinically evident...

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PMID: 10417127
DOI: 10.1128/iai.67.8.3703-3713.1999

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