Article

RIDDEN: Data-driven inference of receptor activity from transcriptomic data

2024-12-07

Abstract excerpt

Intracellular signaling initiated from ligand bound receptors plays a fundamental role in both physiological regulation and development of disease states, making receptors one of the most frequent drug targets. Systems level analysis of receptor activity can help to identify cell and disease type specific receptor activity alterations. While recently several computational methods have been developed to analyse lig...

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Identifiers and source

Literature Corpus work: a8214c70-c54c-5cb6-a24a-dbcfda66d247
DOI: 10.1101/2024.12.03.626558

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