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Development of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of Colorectal Cancer.

Alternatives to laboratory animals : ATLA - 1 Jul 2022

van den Driest Lisa, Johnson Caroline H, Rattray Nicholas J W, Rattray Zahra

Abstract excerpt

Colorectal cancer (CRC) is a global cause of cancer-related mortality driven by genetic and environmental factors which influence therapeutic outcomes. The emergence of next-generation sequencing technologies enables the rapid and extensive collection and curation of genetic data for each cancer type into clinical gene expression biobanks. We report the application of bioinformatics tools for investigating the...

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PMID: 35765262
DOI: 10.1177/02611929221107546

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