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Increased CCL2/CCR2 axis promotes tumor progression by increasing M2 macrophages in MYC/BCL2 double-expressor diffuse large B-cell lymphoma

2024-04-10

Abstract excerpt

<title>Abstract</title> <p>The pathogenesis of MYC and BCL2 double expressor diffuse large B-cell lymphoma (DE-DLBCL) remains unclear. To investigate how MYC and BCL2 contribute to tumor aggressiveness, we analyzed tumors from 14 patients each with DE- and non-DE-DLBCL patients by whole transcriptome sequencing. Validation was performed using publicly available datasets, tumor tissues from 126 patients, DLBCL cel...

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Literature Corpus work
a80f5826-3216-5143-977f-6daafe13186e
DOI
10.21203/rs.3.rs-4220323/v1
Open publication

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Increased CCL2/CCR2 axis promotes tumor progression by increasing M2 macrophages in MYC/BCL2 double-expressor diffuse large B-cell lymphomaDOI 10.21203/rs.3.rs-4220323/v1
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