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Article

An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates.

Scientific reports - 22 Nov 2019

Decano Arun Gonzales, Downing Tim

Abstract excerpt

Escherichia coli ST131 is a major cause of infection with extensive antimicrobial resistance (AMR) facilitated by widespread beta-lactam antibiotic use. This drug pressure has driven extended-spectrum beta-lactamase (ESBL) gene acquisition and evolution in pathogens, so a clearer resolution of ST131's origin, adaptation and spread is essential. E. coli ST131's ESBL genes are typically embedded in mobile genetic...

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Identifiers

PMID: 31758048
DOI: 10.1038/s41598-019-54004-5
PMCID: PMC6874702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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