Back to search

Article

Complete assembly of <i>Escherichia coli</i> ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts

2019-02-22

Abstract excerpt

The incidence of infections caused by extraintestinal Escherichia coli (ExPEC) is rising globally, which is a major public health concern. ExPEC strains that are resistant to antimicrobials have been associated with excess mortality, prolonged hospital stays and higher healthcare costs. E. coli ST131 is a major ExPEC clonal group worldwide with variable plasmid composition, and has an array of genes enabling ant...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
934a7515-710f-5ae8-baa8-ad8d7aa7dc4c
DOI
10.1101/558635
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Complete assembly of <i>Escherichia coli</i> ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contextsDOI 10.1101/558635
Genomic surveillance of <i>Escherichia coli</i> ST131 identifies local expansion and serial replacement of subclonesSemantic proximity
Short- and Long-Read Sequencing Reveals the Presence and Evolution of an IncF Plasmid Harboring bla CTX-M-15 and bla CTX-M-27 Genes in Escherichia coli ST131Semantic proximity
An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates.Semantic proximity
Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131.Semantic proximity
High contiguity genome sequence of a multidrug-resistant hospital isolate of Enterobacter hormaecheiSemantic proximity
Plasmids Shape the Diverse Accessory Resistomes of Escherichia coli ST131Semantic proximity
The epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx.Semantic proximity
Global dissemination of a multidrug resistant Escherichia coli clone.Semantic proximity
Mapping the evolutionary path towards multi-drug resistance in the pandemic <i>Escherichia coli</i> ST131 lineageSemantic proximity
Plasmids shape the diverse accessory resistomes of <i>Escherichia coli</i> ST131Semantic proximity
Evolution of extended-spectrum β-lactamase-producing ST131 <i>Escherichia coli</i> at a single hospital over 15 yearsSemantic proximity
Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131Semantic proximity
Select a neighboring publication to make it the new centre.