Article
Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131.
mBio - 26 Apr 2016
Ben Zakour Nouri L, Alsheikh-Hussain Areej S, Ashcroft Melinda M, Khanh Nhu Nguyen Thi, Roberts Leah W, Stanton-Cook Mitchell, Schembri Mark A, Beatson Scott A
Abstract excerpt
UNLABELLED: Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli clone worldwide and a major cause of urinary tract and bloodstream infections. Although originally identified through its association with the CTX-M-15 extended-spectrum β-lactamase resistance gene, global genomic epidemiology studies have failed to resolve the geographical and temporal origin of the ST131...
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