Article
Global dissemination of a multidrug resistant Escherichia coli clone.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 2014
Petty Nicola K, Ben Zakour Nouri L, Stanton-Cook Mitchell, Skippington Elizabeth, Totsika Makrina, Forde Brian M, Phan Minh-Duy, Gomes Moriel Danilo, Peters Kate M, Davies Mark, Rogers Benjamin A, Dougan Gordon, Rodriguez-Baño Jesús, Pascual Alvaro, Pitout Johann D D, Upton Mathew, Paterson David L, Walsh Timothy R, Schembri Mark A, Beatson Scott A
Abstract excerpt
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a high proportion of urinary tract and bloodstream infections. The rapid emergence and successful spread of E. coli ST131 is strongly associated with several factors, including resistance to fluoroquinolones, high virulence gene content, the possession of the type 1 fimbriae FimH30 allele, and...
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