Article

Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia

2023-11-17

Abstract excerpt

The term cancer immunoediting describes the dual role by which the immune system can suppress and promote tumour growth and is divided into three phases: elimination, equilibrium and escape. The role of NK cells has mainly been attributed to the elimination phase. Here we show that NK cells play a role in all three phases of cancer immunoediting. Extended co-culturing of DNA barcoded mouse BCR/ABL p185+ B acute l...

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Literature Corpus work: a7f8cd4e-63c5-5055-9030-43e3e049fefa
DOI: 10.1101/2023.11.16.567430

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