A structural, genetic and clinical comparison of CAR-T cells and CAR-NK cells: companions or competitors?

doi:10.3389/fimmu.2024.1459818

Article

A structural, genetic and clinical comparison of CAR-T cells and CAR-NK cells: companions or competitors?

4 Oct 2024

Abstract excerpt

In recent years, following the groundbreaking achievements of chimeric antigen receptor (CAR) T cell therapy in hematological cancers, and advancements in cell engineering technologies, the exploration of other immune cells has garnered significant attention. CAR-Therapy extended beyond T cells to include CAR natural killer (NK) cells and CAR-macrophages, which are firmly established in the clinical trial...

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