Article

Altered oscillatory coupling reflects possible inhibitory interneuron dysfunction in Rett syndrome

2025-07-21

Abstract excerpt

Rett syndrome is a rare neurodevelopmental disorder caused primarily by pathogenic variants in the MECP2 gene, leading to lifelong cognitive impairments. To understand the broad neural disruptions in Rett syndrome, it is essential to examine large-scale brain dynamics at the level of neural oscillations. Phase-amplitude coupling—a form of cross-frequency interaction that supports information integration across te...

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Literature Corpus work: a7d9f02d-286a-520a-83e5-4cdeff3077f5
DOI: 10.1101/2025.07.21.25331927

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