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Unstable Slow Oscillations Couple with Epileptogenic Fast-Rhythm Bistability in Sleep-Related Epilepsy: An SEEG Study

2025-03-26

Abstract excerpt

<h4>Objective</h4> While slow waves in δ (0.5–4 Hz) characterize NREM sleep, in patients with sleep-related epilepsy, seizures most frequently emerge during NREM stage 2, known to be promoted by δ-band instability. Meanwhile, the epileptogenic zone (EZ) shows localized bistability in β–γ band (15–200 Hz) neuronal oscillations—indicating a catastrophic shift toward seizure. We aim to clarify the mechanistic link b...

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Literature Corpus work
8566537e-545e-523e-a955-a9ba50229fc9
DOI
10.1101/2025.03.25.642592
Open publication

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Unstable Slow Oscillations Couple with Epileptogenic Fast-Rhythm Bistability in Sleep-Related Epilepsy: An SEEG StudyDOI 10.1101/2025.03.25.642592
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