Article

Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles

2024-06-25

Abstract excerpt

<title>Abstract</title> <p>Hereditary SDHB-mutant pheochromocytomas (PC) and paragangliomas (PG) are rare tumours with a high propensity to metastasize although their clinical behaviour is unpredictable. To characterize the genomic landscape of these tumours and identify metastasis biomarkers, we performed multi-omic analysis on 94 tumours from 79 patients using seven molecular methods. Sympathetic (chromaffin ce...

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Literature Corpus work: a76c644f-2015-55fc-bc0b-cead35bc96bb
DOI: 10.21203/rs.3.rs-4410500/v1

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