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Biomarkers Improving Genetic and Metastatic Disease Prediction in Paraganglioma: Insights From a Prospective Study

14 Nov 2024

Abstract excerpt

CONTEXT AND OBJECTIVE: Identifying the risk of malignancy and genetic status in primary paraganglioma or pheochromocytoma (PPGL) is a key challenge. The aim was to assess the diagnostic accuracy of genomic, metabolomic and histopathological biomarkers for predicting metastatic and genetic status. DESIGN, SETTING, AND PATIENTS: COMETE-TACTIC is a prospective study (NCT02672020) conducted from November 2015 to...

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PMID: 39541377
DOI: 10.1210/clinem/dgae797

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