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Article

Recent progress in molecular classification of phaeochromocytoma and paraganglioma.

Best practice & research. Clinical endocrinology & metabolism - 1 Dec 2024

Boehm Emma, Gill Anthony J, Clifton-Bligh Roderick, Tothill Richard W

Abstract excerpt

Phaeochromocytomas (PC) and paragangliomas (PG) are neural crest cancers with high heritability. Recent advances in molecular profiling, including multi-omics and single cell genomics has identified up to seven distinct molecular subtypes. These subtypes are defined by mutations involving hypoxia-inducible factors (HIFs), Krebs cycle, kinase and WNT signalling, but are also defined by chromaffin differentiation...

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Source

Identifiers

PMID: 39271378
DOI: 10.1016/j.beem.2024.101939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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