Article

Obesity phenotypes are preserved in intestinal stem cell enteroids from morbidly obese patients

2020-05-31

Abstract excerpt

Obesity and obesity-related comorbidities are significant health care challenges. Bariatric surgery (BS) is the most effective therapy for treating obesity and type 2 diabetes. A barrier in the development of therapeutic alternatives is incomplete mechanistic understanding of the benefits of BS and the lack of human intestinal models that recapitulate the pathophysiology of obesity. Using adult intestinal stem cel...

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Literature Corpus work: a7681da8-f962-5564-a5d5-26f26d0ab0af
DOI: 10.1101/2020.05.29.123737

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