Article

Dysregulated intestinal nutrient absorption in obesity is associated with epigenomic alterations in epithelia

2024-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Obesity is an epidemic with myriad health effects, but little is understood regarding individual obese phenotypes and how they may respond to therapy. Epigenetic changes associated with obesity have been detected in blood, liver, pancreas, and adipose tissues. Previous work using human organoids found that dietary glucose hyperabsorption is a steadfast trait in cultures derived from some obese s...

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Literature Corpus work: 2f50514a-56c9-5bdf-b993-2fe911a428a5
DOI: 10.1101/2024.05.06.591758

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