Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gastrointestinal weight-loss surgery: glimpses at the molecular level.

Drug discovery today - 1 Jul 2013

Freudenberg Johannes M, Rajpal Neetu, Way James M, Magid-Slav Michal, Rajpal Deepak K

Abstract excerpt

Pharmacotherapy for obesity remains a key challenge, and gastrointestinal weight-loss surgery remains a preferred option to help reduce excess body weight along with resolution of several comorbidities associated with obesity. This offers a unique opportunity to study the underlying mechanisms of gastro-intestinal weight-loss surgery to develop effective and less invasive long-term therapeutic interventions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bariatric Surgery
Share to Computational Biology
Share to Drug Discovery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolomics

Share to Molecular Targeted Therapy

Share to Obesity

Share to Proteomics

Share to Weight Loss

Source

Identifiers

PMID: 23266345
DOI: 10.1016/j.drudis.2012.12.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gastrointestinal weight-loss surgery: glimpses at the molecular level.PMID 23266345Read ↗

A low protein diet drives short-and long-term improvements in metabolic health in a mouse model of sleeve gastrectomySemantic proximity Read ↗

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissueSemantic proximity Read ↗

Emerging Trends in Endoscopic Bariatric Therapies: Personalization Through Genomics and Synergistic PharmacotherapySemantic proximity Read ↗

Mechanisms and Outcomes of Metabolic Surgery in Type 2 DiabetesSemantic proximity Read ↗

Rapid and long-lasting remodelling of the blood transcriptome following bariatric surgerySemantic proximity Read ↗

Bariatric Surgery and Precision Nutrition.Semantic proximity Read ↗

Microbiome and Genetic Predictors of Weight Loss 12 Months Post Sleeve Gastrectomy: Insights from a Pilot Retrospective Cohort StudySemantic proximity Read ↗

Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric SurgerySemantic proximity Read ↗

Integrative analyses of biomarkers and pathways for adipose tissue after bariatric surgerySemantic proximity Read ↗

Early changes in immune cell metabolism and function are a hallmark of sleeve gastrectomy: a prospective human studySemantic proximity Read ↗

From one-size-fits-all to phenotype-based pharmacotherapy: How far are we in obesity management?Semantic proximity Read ↗

Baseline metabolomic profile as potential biomarker for weight change after Roux-en-Y gastric bypass (RYGB) surgerySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.