Back to search

Article

Rolling the evolutionary dice: <i>Neisseria</i> commensals as proxies for elucidating the underpinnings of antibiotic resistance mechanisms and evolution in human pathogens

2023-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Species within the genus Neisseria are especially adept at sharing adaptive allelic variation across species’ boundaries, with commensal species repeatedly transferring resistance to their pathogenic relative N. gonorrhoeae . However, resistance in commensal Neisseria is infrequently characterized at both the phenotypic and genotypic levels, limiting our ability to predict novel and potential...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
45cf093e-38b8-5e33-8681-1f277e6c07be
DOI
10.1101/2023.09.26.559611
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Rolling the evolutionary dice: <i>Neisseria</i> commensals as proxies for elucidating the underpinnings of antibiotic resistance mechanisms and evolution in human pathogensDOI 10.1101/2023.09.26.559611
Constrained evolutionary paths to macrolide resistance in a <i>Neisseria</i> commensal converge on ribosomal genes through sequence duplicationSemantic proximity
Exploration of the <i>Neisseria</i> resistome reveals resistance mechanisms in commensals that may be acquired by <i>N. gonorrhoeae</i> through horizontal gene transferSemantic proximity
Put your money where your mouth is: Surveillance of antibiotic resistance within the commensal <i>Neisseria</i>Semantic proximity
<i>In vitro</i> evolution of ciprofloxacin resistance in <i>Neisseria</i> commensals and derived mutation population dynamics in natural <i>Neisseria</i> populationsSemantic proximity
Antimicrobial Resistance Profiles of Human Commensal <em>Neisseria</em> SpeciesSemantic proximity
Re-visiting the potential impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the selection of doxycycline resistance in <i>Neisseria</i> commensalsSemantic proximity
Antibiotic resistance in Neisseria gonorrhoeae : origin, evolution, and lessons learned for the futureSemantic proximity
Genetic determinants of antibiotic resistance and the evolution of trade-offs during adaptation in a single patientSemantic proximity
Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution.Semantic proximity
The Synergistic Armory: A Global Genome-Wide Association Study Reveals the Integrated Mechanisms of Azithromycin Resistance in Neisseria gonorrhoeae.Semantic proximity
Increased antibiotic susceptibility in <i>Neisseria gonorrhoeae</i> through adaptation to the cervical environmentSemantic proximity
Doxycycline Post-Exposure Prophylaxis Could Induce Cross-Resistance to Other Classes of Antimicrobials in Commensal Neisseria Species: An Analysis of Commensal <em>Neisseria</em> spp. in JapanSemantic proximity
Select a neighboring publication to make it the new centre.