Article

Tau load in select brainstem neurons predicts the severity and nature of balance deficits in the absence of cell death

2024-10-14

Abstract excerpt

Patients with tauopathies present with profoundly different clinical symptoms 1 , even within the same disorder 2 . A central hypothesis in the field, well-supported by biomarker studies 3,4 and post-mortem pathology 5–7 , is that clinical heterogeneity reflects differential degeneration of vulnerable neuronal populations responsible for specific neurological functions. Recent work has revealed mechanisms unde...

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Literature Corpus work: a75737da-1064-53e2-9588-73e7751b4386
DOI: 10.1101/2024.10.14.618073

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