Article
Development of CAR-T Cell Therapy for B-ALL Using a Point-of-Care Approach
2019-09-16
Abstract excerpt
Recently approved by the FDA and European Medicines Agency, CAR-T cell therapy is a new treatment option for B-cell malignancies. Currently, CAR-T cells are manufactured in centralized facilities and face bottlenecks like complex scaling up, high costs and logistic operations. These difficulties are mainly related to the use of viral vectors and the requirement to expand CAR-T cells to reach the therapeutic dose....
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Identifiers and source
- Literature Corpus work
- a74c4846-f170-5c31-9f70-e53fb3c68e0f
- DOI
- 10.1101/770297
