Article

Conformoreplication and the Conformotype: Formalising Alt-F Proteins as a Conceptual Extension of the Central Dogma and a Third Tier of Molecular Inheritance

2026-04-27

Abstract excerpt

Protein conformational inheritance is documented across bacteria, fungi, and neurons, and while several authors have argued for its conceptual inclusion in molecular inheritance frameworks, a concise, widely adopted formal vocabulary that unifies these literatures remains lacking. Naming by pathological outcome rather than mechanism has partitioned prion disease research, adaptive conformational biology, and prote...

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Literature Corpus work: a7467cbe-e375-55da-aa69-7770bfc6c388
DOI: 10.20944/preprints202604.1911.v1

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