Article

Conformoreplication and the Conformotype: Formalising Alt-F Proteins as a Conceptual Extension of the Central Dogma and a Third Tier of Molecular Inheritance

2026-07-22

Abstract excerpt

Protein conformational inheritance is documented across bacteria, fungi, and neurons, and while several authors have argued for its conceptual inclusion in molecular inheritance frameworks, a concise, widely adopted formal vocabulary that unifies these literatures remains lacking. Naming by pathological outcome rather than mechanism has partitioned prion disease research, adaptive conformational biology, and prote...

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Literature Corpus work: 8d2d75d0-6add-5f10-b34d-d433fecee9dd
DOI: 10.20944/preprints202604.1911.v2

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