Article

A chemogenomic approach seems indispensable for effective treatment of amyotrophic lateral sclerosis

2021-01-29

Abstract excerpt

ALS is a fatal untreatable disease involving degeneration of motor neurons. Μultiple causative genes encoding proteins with versatile functions have been identified indicating that diverse biological pathways lead to ALS. Gene and stem cell-based therapies are not expected to enter clinical practice anytime soon. Thus, chemical entities represent a promising choice to delay ALS progression, attenuate symptoms and/...

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Literature Corpus work: a6db7dd9-e6eb-59da-af96-5355a5323fa3
DOI: 10.22541/au.161193502.21521333/v1

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