Article
[Amyotrophic lateral sclerosis and frontotemporal dementia-On the way to common gene-specific treatment approaches].
Der Nervenarzt - 1 Dec 2021
Anderl-Straub Sarah, Schuster Joachim, Dorst Johannes, Ludolph Albert C
Abstract excerpt
BACKGROUND: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share common neuropathological features and in the case of a gene mutation, also a genetic cause. To date five ALS-FTD genes are described in the literature in addition to other rare variants. OBJECTIVE: The current state of research on treatment options for ALS and FTD is presented and an outlook on possible gene-specific...
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