Article

A Human Vocal Fold Organ-On-Chip for Studying Platform-Dependent Mucosal Responses to Particulate Matter

2026-06-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Coarse particulate matter (PM 10 ) deposits at the vocal fold (VF) mucosa, yet upper airway responses remain poorly characterized. Existing in vitro VF models use monocultures that lack the stratified epithelium, lamina propria, and physiological perfusion. We developed a chip-based co-culture model of human VF mucosa and applied it to acute PM 10 exposure. <h4>Methods</...

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Literature Corpus work: a6d83759-4d42-57f8-b4f1-f517d7f883fe
DOI: 10.64898/2026.05.29.728871

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