Article

Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

2023-04-03

Abstract excerpt

Human lung organoids (HLOs) are increasingly used to model development and infectious diseases, however their ability to recapitulate functional pulmonary tissue response to nanomaterial (NM) exposures has yet to be demonstrated. Here, we established a lung organoid exposure model that utilises microinjection to present NMs into the lumen of organoids. Our model assures efficient, reproducible and controllable exp...

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Literature Corpus work: e02b9ff7-c851-5a9a-904d-bd75407749a1
DOI: 10.1101/2023.03.30.534957

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