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Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure

24 Sept 2019

Abstract excerpt

Development of treatments for vocal dysphonia has been inhibited by lack of human vocal fold (VF) mucosa models because of difficulty in procuring VF epithelial cells, epithelial cells' limited proliferative capacity and absence of cell lines. Here we report development of engineered VF mucosae from hiPSC, transfected via TALEN constructs for green fluorescent protein, that mimic development of VF epithelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31551422
DOI: 10.1038/s41467-019-12069-w

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