Article

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

2019-07-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Enteroendocrine cells (EECs) of the gastro-intestinal tract sense gut luminal factors and release peptide hormones or serotonin (5-HT) to coordinate energy uptake and storage. Our goal is to decipher the gene regulatory networks controlling EECs specification from enteroendocrine progenitors. In this context, we studied the role of the transcription factor Rfx6 which had been...

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Literature Corpus work: a6d6b68c-057d-558f-8800-c1dabf2e1eb5
DOI: 10.1101/704924

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