Article

Best of Both Worlds? Optimising Graph-Based Antimicrobial Resistance Gene Profiling in Long and Short-Read Metagenomes

2025-12-26

Abstract excerpt

Environmental surveillance using metagenomic sequencing offers a powerful way to track emerging and mobile antimicrobial resistance (AMR) genes and inform public health mitigation strategies. Read-based analysis tools can sensitively detect AMR genes in metagenomes but provide little information about the surrounding genome. This prevents easily linking detected genes with particular host species or mobile genetic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a69a90f9-7c0d-5462-ab5e-8a18bf5251fc
DOI: 10.64898/2025.12.25.693921

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Best of Both Worlds? Optimising Graph-Based Antimicrobial Resistance Gene Profiling in Long and Short-Read MetagenomesDOI 10.64898/2025.12.25.693921Read

Sarand: Exploring Antimicrobial Resistance Gene Neighborhoods in Complex Metagenomic Assembly GraphsSemantic proximity Read

Accurate and fast graph-based pangenome annotation and clustering with ggCallerSemantic proximity Read

Exploring differences across pangenome-graph representations using <i>Escherichia coli</i> O157:H7 as a modelSemantic proximity Read

Resistome SNP Calling via Read Colored de Bruijn GraphsSemantic proximity Read

Knowledge Graph-Based Framework for Detecting Horizontal Gene Transfer Events Driving Antimicrobial ResistanceSemantic proximity Read

Comparative metagenomics using pan-metagenomic graphsSemantic proximity Read

Influence of Sequencing Technology on Pangenome-level Analysis and Detection of Antimicrobial Resistance Genes in ESKAPE PathogensSemantic proximity Read

Genomics for antimicrobial resistance—progress and future directionsSemantic proximity Read

Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistanceSemantic proximity Read

NanoARG: A web service for identification of antimicrobial resistance elements from nanopore-derived environmental metagenomesSemantic proximity Read

AMR-GNN: A multi-representation graph neural network framework to enable genomic antimicrobial resistance predictionSemantic proximity Read

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory studySemantic proximity Read