Article

Metabolites from plasma-like medium fuel nitrogen metabolism and influence proliferation in <i>Leptospira interrogans</i>

2026-03-13

Abstract excerpt

Leptospirosis, caused by pathogenic Leptospira spp. such as L. interrogans , is a bacterial zoonosis of increasing prevalence with no consistently effective treatments in severe cases. We sought to characterize metabolic mechanisms that support L. interrogans infection in the host setting, with the ultimate goal of revealing unexplored therapeutic opportunities. We first established and validated a culture medi...

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Literature Corpus work: a64e7dff-bd3a-5d77-ab0e-f366f55ab2a9
DOI: 10.64898/2026.03.12.711193

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