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Intracellular glutamine fluctuates with nitrogen availability and regulates <i>Mycobacterium smegmatis</i> biofilm formation

2025-06-19

Abstract excerpt

Biofilm formation allows pathogenic nontuberculous mycobacteria (NTM) to adhere to household plumbing systems and has been observed in vivo during human infection. Glucose drives NTM aggregation in vitro , and ammonium inhibits it, but the regulatory systems controlling this early step in biofilm formation are not understood. Here, we show that a variety of carbon and nitrogen sources have similar impacts on agg...

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Identifiers and source

Literature Corpus work
73e13e60-223c-52d1-9c12-89fccd2aa109
DOI
10.1101/2025.06.18.660496
Open publication

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Intracellular glutamine fluctuates with nitrogen availability and regulates <i>Mycobacterium smegmatis</i> biofilm formationDOI 10.1101/2025.06.18.660496
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