Host-like Temperature Unlocks Glucose Uptake and Metabolism in Pathogenic <i>Leptospira</i>

Abstract excerpt

Pathogenic Leptospira transitions between environmental reservoirs and mammalian hosts, expose the bacterium to distinct temperature conditions. Although Leptospira is generally considered to rely its growth primarily on long-chain fatty acids and to have limited capacity to use glucose, whether host-like temperature alters glucose-associated metabolic capacity remains unclear. Here, we used transcriptome-integr...

Topics

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• Biomass
• Citric Acid Cycle
• Gene Regulatory Networks
• Glucose
• Iron
• Molecular Weight
• Pyruvates
• Yersinia pseudotuberculosis

Identifiers and source

Literature Corpus work

03a762dd-a2a5-5a42-9b1b-80bc8ce3cdb2

DOI

10.64898/2026.07.24.740548