Article

AAV-Mediated <i>In Vivo</i> CAR Gene Therapy for Targeting Human T Cell Leukemia

2021-02-15

Abstract excerpt

Chimeric antigen receptor (CAR) T cell therapy is the most active field in immuno-oncology and brings substantial benefit to patients with B cell malignancies. However, the complex procedure for CAR T cell generation hampers its widespread applications. Here, we describe a novel approach in which human CAR T cells can be generated within the host upon injecting an Adeno-associated virus (AAV)vector carrying the CA...

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Literature Corpus work: a64cbd78-7cef-5c83-8c4f-6fb3bac43c0c
DOI: 10.1101/2021.02.15.431201

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