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Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice

2024-09-23

Abstract excerpt

<h4>Background</h4> Targeting multiple risk factors through preventive interventions can halt the onset or progression of dementia. The clinical efficacy of this approach was shown in the multimodal FINGER trial, yet knowledge of the underlying biological mechanisms is limited. In the current study, we applied for the first time a multimodal lifestyle intervention in mice to study effects on cognition and associa...

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Literature Corpus work
a63e8dcc-1dab-5f44-b048-6785d78bda2a
DOI
10.1101/2024.09.23.614418
Open publication

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Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female miceDOI 10.1101/2024.09.23.614418
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