Article

Epigenetic Conditioning Induces Intergenerational Resilience to Dementia in a Mouse Model of Vascular Cognitive Impairment

2021-06-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Vascular cognitive impairment and dementia (VCID), which occurs immediately or in delayed fashion in 25-30% of stroke survivors, or secondary to chronic cerebral hypoperfusion, is the second leading cause of dementia following Alzheimer’s disease. To date, efficacious therapies are unavailable. We have shown previously in mice that repetitive hypoxic preconditioning (RHC) in...

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Literature Corpus work: 1cd0ac51-a42c-51c6-bc6c-1155fc747b7f
DOI: 10.1101/2021.06.16.448715

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