Article

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

2021-02-24

Abstract excerpt

<h4>Summary</h4> Over the past 20 years, the emergence of three highly pathogenic coronaviruses (CoV) – SARS-CoV, MERS-CoV, and most recently SARS-CoV-2 – has shown that CoVs pose a serious risk to human health and highlighted the importance of developing effective therapies against them. Similar to other viruses, CoVs are dependent on host factors for their survival and replication. We hypothesized that evolutio...

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Literature Corpus work: a6fb5f4a-7b71-58ee-98cf-52b365762caf
DOI: 10.1101/2021.02.24.432634

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