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Increased viral tolerance mediates by antiviral RNA interference in bat cells

1 Aug 2024

Abstract excerpt

Bats harbor highly virulent viruses that can infect other mammals, including humans, posing questions about their immune tolerance mechanisms. Bat cells employ multiple strategies to limit virus replication and virus-induced immunopathology, but the coexistence of bats and fatal viruses remains poorly understood. Here, we investigate the antiviral RNA interference pathway in bat cells and discover that they have...

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PMID: 39102336
DOI: 10.1016/j.celrep.2024.114581

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